Efficient microwave-assisted synthesis of multivalent dendrimeric peptides using cycloaddition reaction (click) chemistry.

نویسندگان

  • Dirk T S Rijkers
  • G Wilma van Esse
  • Remco Merkx
  • Arwin J Brouwer
  • Hans J F Jacobs
  • Roland J Pieters
  • Rob M J Liskamp
چکیده

Multivalent dendrimeric peptides were synthesized via a microwave-assisted Huisgen 1,3-dipolar cycloaddition between azido peptides and dendrimeric alkynes in yields ranging from 46 to 96%.

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عنوان ژورنال:
  • Chemical communications

دوره 36  شماره 

صفحات  -

تاریخ انتشار 2005